Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1365 | Pituitary Clinical | ICEECE2012

IGF1 as a risk factor for insulin resisitance and glucose intolerance in acromegaly

Niculescu D. , Purice M. , Lichiardopol R. , Coculescu M.

Introduction: In normal subjects GH is a hyperglycemic hormone as opposed to insulin-like growth factor 1 (IGF1). Active acromegaly is associated with insulin resistance (IR) and glucose intolerance although both GH and IGF1 are elevated. Our objective was to assess whether GH, IGF1 or both are risk factors for IR and glucose intolerance in acromegaly.Methods: Basal serum IGF1 and GH, glucose and insulin during an oral glucose tolerance test were measure...

ea0011p633 | Neuroendocrinology and behaviour | ECE2006

Hormone therapy effects on sleep and dreams in menopausal women

Rasanu C , Niculescu D , Botusan I , Filip O , Coculescu M

Introduction and objective: This study aims to report if hormone therapy modifies sleep architecture and dreams in menopausal women. Women with no hormone therapy for flushes usually present sleep deprivation and daily sleepiness as a result of nocturnal arousals. Estrogen and progesterone brain receptors can influence memory and cognition processes. Dreams modulators are cognition, socio-cultural factors, personality and brain physiology (REM/NREM percents, circadian influenc...

ea0009p105 | Endocrine tumours and neoplasia | BES2005

Clinically mute adrenal tumours - study of 63 cases

Gheorghiu M , Hortopan D , Dumitrascu A , Stefanescu A , Trifanescu R , Niculescu D , Coculescu M

Background: There is a large agreement that most of the incidentally discovered, clinically mute adrenal masses are incidentalomas - non-functioning tumours, which have to be explored in order to differentiate the adrenal carcinoma.Material and methods: We studied the prevalence and characteristics of clinically mute adrenal tumours and the evolution of adrenal incidentalomas, with the approval of the local Ethical Committee, in 123 patients with adrenal...